Establishment of a Vietnamese ethnicity induced pluripotent stem cell line (VRISGi001-A) from umbilical cord blood hematopoietic stem cells under a feeder-free system

dc.contributor.author	Nguyen, Xuan Hung
dc.contributor.author	Nguyen, Thi Thao
dc.contributor.author	Nguyen, Hong Nhung
dc.contributor.author	Tran, Thi Tuyet Trinh
dc.date.accessioned	2024-10-24T06:55:27Z
dc.date.available	2024-10-24T06:55:27Z
dc.date.issued	2021-04-05
dc.identifier.uri	https://vinspace.edu.vn/handle/VIN/281
dc.description.abstract	VRISGi001-A, from cord-blood derived CD34 + hematopoietic stem cells (HSCs) of a 35 year old healthy woman under cGMP-compliant process. For the hiPSC induction, three Sendai virus vectors carrying four reprogramming factors including c-MYC, SOX2, KLF4, and OCT3/4 were delivered into CD34+ HSCs. The VRISGi001-A cell line expresses the majority of the pluripotent markers and differentiates in vitro into derivatives of three germ layers. The availability of the Vietnamese hiPSC line could contribute to the improvement of inadequate genetic diversity in the currently available hiPSC lines.	en_US
dc.language.iso	en_US	en_US
dc.subject	vietnamese human induced pluripotent stem cell	en_US
dc.subject	yamanaka factor	en_US
dc.subject	sendai viru	en_US
dc.title	Establishment of a Vietnamese ethnicity induced pluripotent stem cell line (VRISGi001-A) from umbilical cord blood hematopoietic stem cells under a feeder-free system	en_US
dc.type	Article	en_US