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Iloprost Attenuates Oxidative Stress-Dependent Activation of Collagen Synthesis Induced by Sera from Scleroderma Patients in Human Pulmonary Microvascular Endothelial Cells
(2021-08-05)
Endothelial cell injury is an early event in the pathogenesis of systemic sclerosis (SSc), with oxidative stress being a key trigger of SSc-associated vasculopathy. This study demonstrates that circulating factors in the ...
Oxidative stress related to plasmalemmal and mitochondrial phosphate transporters in vascular calcification
(2022-03-02)
Inorganic phosphate (Pi) is crucial for cellular functions, but excessive Pi can lead to serious complications, including vascular calcification. Recent studies have highlighted the role of oxidative stress in the progression ...
Oxidative stress by Ca2+ overload is critical for phosphate-induced vascular calcification
(2020-12)
Hyperphosphatemia is a significant risk factor for vascular calcification, which is closely linked to increased cardiovascular morbidity and mortality. Recent research indicates that oxidative stress induced by high inorganic ...
Oxidative stress related to plasmalemmal and mitochondrial phosphate transporters in vascular calcification
(2022-03-02)
Inorganic phosphate (Pi) is essential for maintaining cellular function but excess of Pi leads to serious complications, including vascular calcification. Accumulating evidence suggests that oxidative stress contributes ...
Iloprost attenuates oxidative stress-dependent activation of collagen synthesis induced by sera from scleroderma patients in human pulmonary microvascular endothelial cells
(2021-08-02)
Endothelial cell injury is an early event in systemic sclerosis (SSc) pathogenesis and several studies indicate oxidative stress as the trigger of SSc-associated vasculopathy. Here, we show that circulating factors present ...
Oxidative stress by Ca2+ overload is critical for phosphate-induced vascular calcification
(2020-11)
Hyperphosphatemia is the primary risk factor for vascular calcification, which is closely associated with cardiovascular morbidity and mortality. Recent evidence showed that oxidative stress by high inorganic phosphate ...