Browsing by Author "Than, Uyen Thi Trang"
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Cytokine-primed umbilical cord mesenchymal stem cells enhanced therapeutic effects of extracellular vesicles on osteoarthritic chondrocytes
Nguyen, Thu Huyen; Dao, Huy Hoang; Duong, Chau Minh; Nguyen, Xuan Hung; Hoang, Diem Huong; Do, Xuan Hai; Truong, Trung Quang; Nguyen, Tu Dac; Nguyen, Thanh Liem; Than, Uyen Thi Trang (2022-10)In recent years, extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) have emerged as a potential cell-free therapy against osteoarthritis (OA). Thus, we investigated the therapeutic effects of EVs released ... -
Cytokine-primed umbilical cord mesenchymal stem cells enhanced therapeutic effects of extracellular vesicles on osteoarthritic chondrocytes
Nguyen, Thu Huyen; Dao, Huy Hoang; Duong, Chau Minh; Nguyen, Xuan Hung; Hoang, Diem Huong; Do, Xuan Tai; Truong, Trung Quang; Nguyen, Tu Dac; Nguyen, Thanh Liem; Than, Uyen Thi Trang (2022-10-27)In recent years, extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) have emerged as a potential cell-free therapy against osteoarthritis (OA). Thus, we investigated the therapeutic effects of EVs released ... -
Detection of sFas, sCD137, and IL-27 cytokines as potential biomarkers for hepatocellular carcinoma diagnosis
Do, Xuan Hai; Le, Thi Mai; Nguyen, Thu Huyen; Le, Thanh Thien; Nguyen, Xuan Hung; Mai, Thanh Binh; Hoang, Thi My Nhung; Than, Uyen Thi Trang (2023-05-26)Purpose: Hepatocellular carcinoma (HCC), a prevalent type of liver cancer, is mainly diagnosed in the advanced stage, leading to a high mortality rate. Recent advances have identified peripheral cytokines as a potential ... -
Detection of sFas, sCD137, and IL-27 Cytokines as Potential Biomarkers for Hepatocellular Carcinoma Diagnosis
Do, Xuan-Hai; Le, Mai Thi; Nguyen, Thu Huyen; Le, Thanh Thien; Nguyen, Xuan Hung; Mai, Thanh Binh; Hoang, Thi My Nhung; Than, Uyen Thi Trang (2023)Purpose: Hepatocellular carcinoma (HCC), a prevalent type of liver cancer, is mainly diagnosed in the advanced stage, leading to a high mortality rate. Recent advances have identified peripheral cytokines as a potential ... -
Detection of sFas, sCD137, and IL-27 cytokines as potential biomarkers for hepatocellular carcinoma diagnosis
Do, Xuan Hai; Le, Thi Mai; Nguyen, Thu Huyen; Le, Thanh Thien; Nguyen, Xuan Hung; Mai, Thanh Binh; Hoang, Thi My Nhung; Than, Uyen Thi Trang (2023-05-26)Purpose: Hepatocellular carcinoma (HCC), a prevalent type of liver cancer, is mainly diagnosed in the advanced stage, leading to a high mortality rate. Recent advances have identified peripheral cytokines as a potential ... -
Differential Cytotoxicity of Curcumin-Loaded Micelles on Human Tumor and Stromal Cells
Do, Xuan Hai; Hoang, My Hanh Thi; Vu, Anh Tuan; Nguyen, Lai Thanh; Bui, Dung Thi Thuy; Dinh, Duy Thanh; Nguyen, Xuan Hung; Than, Uyen Thi Trang; Mai, Hien Thi; To, Thuy Thanh; Nguyen, Tra Ngoc Huong; Hoang, Nhung Thi My (2022-10)Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. ... -
Effects of Extracellular Vesicles Secreted by TGFβ-Stimulated Umbilical Cord Mesenchymal Stem Cells on Skin Fibroblasts by Promoting Fibroblast Migration and ECM Protein Production
Vu, Duc Minh; Nguyen, Van-Tinh; Nguyen, Thu Huyen; Do, Phuong Thi Xuan; Dao, Huy Hoang; Hai, Do Xuan; Le, Nhi Thi; Nguyen, Xuan Hung; Than, Uyen Thi Trang (2022-08)Umbilical cord-derived mesenchymal stem cells (UCMSCs) have been illustrated for their roles in immunological modulation and tissue regeneration through the secretome. Additionally, culture conditions can trigger the ... -
Induction of Antitumor Immunity by Exosomes Isolated from Cryopreserved Cord Blood Monocyte-Derived Dendritic Cells
Nguyen, Thanh Liem; Nguyen, Phong Van; Bui, Thi Hong Hue; Bui, Thi Khanh Van; Hoang, Diem Huong; Le, Thi Huyen; Than, Uyen Thi Trang (2020-03-06)(1) Background: Dendritic cell (DC) vaccination has shown outstanding achievements in cancer treatment, although it still has some adverse side effects. Vaccination with DC-derived exosomes has been thought to overcome the ... -
Induction of antitumor immunity by exosomes isolated from cryopreserved cord blood monocyte-derived dendritic cells
Than, Uyen Thi Trang; Le, Huyen Thi; Hoang, Diem Huong; Nguyen, Xuan-Hung; Pham, Cuong Thi; Bui, Khanh Thi Van; Bui, Hue Thi Hong; Van Nguyen, Phong; Nguyen, Tu Dac; Do, Thu Thi Hoai; Chu, Thao Thi; Bui, Viet Anh (2020-03-01)(1) Background: Dendritic cell (DC) vaccination has shown outstanding achievements in cancer treatment, although it still has some adverse side effects. Vaccination with DC-derived exosomes has been thought to overcome the ... -
Influences of Xeno-Free Media on Mesenchymal Stem Cell Expansion for Clinical Application
Nguyen, Thanh Liem; Bui, Thi Hong Hue; Than, Uyen Thi Trang (2020-09-27)Mesenchymal stem/stromal cells (MSCs) are multipotent somatic stem/progenitor cells that can be isolated from various tissues and have attracted increasing attention from the scientific community. This is due to MSCs showing ... -
Mesenchymal stem cell-derived extracellular vesicles for osteoarthritis treatment: Extracellular matrix protection, chondrocyte and osteocyte physiology, pain and inflammation management
Nguyen, Thu Huyen; Duong, Chau Minh; Nguyen, Xuan-Hung; Than, Uyen Thi Trang (2021-11)Osteoarthritis (OA) is a common degenerative disease that can lead to persistent pain and motion restriction. In the last decade, stem cells, particularly mesenchymal stem cells (MSCs), have been explored as a potential ... -
Optimization of human umbilical cord blood-derived mesenchymal stem cell isolation and culture methods in serum- and xeno-free conditions
Nguyen, Thanh Liem; Tran, Nghia Trung; Than, Uyen Thi Trang; Nguyen, Minh Quang; Tran, Anh Minh; Do, Phuong Thi Xuan; Chu, Thao Thi; Nguyen, Tu Dac; Bui, Viet Anh; Ngo, Tien Anh; Hoang, Van Thanh; Hoang, Nhung Thi My (2022-12)Background: Although umbilical cord blood (UCB) is identified as a source of mesenchymal stem cells (MSCs) with various advantages, the success in cell isolation is volatile. Therefore, it is necessary to optimize methods ... -
Vγ9γδ T Cell Induction by Human Umbilical Cord Blood Monocytes-Derived, Interferon-α-Stimulated Dendritic Cells
Anh, Bui Viet; Chu, Thao Thi; Pham, Cuong Thi; Nguyen, Thuy Thu Thi; Hoang, Diem Huong; Bui, Khanh Thi Van; Bui, Hue Thi Hong; Than, Uyen Thi Trang; Nguyen Dac, Tu; Tran, Hoai Ton Thi; Nguyen, Thanh Lai; Nguyen, Thanh Liem (2020)Dendritic cells (DC) are professional antigen-presenting cells that activate T cells to kill cancer cells. The extracellular products of DCs have also been reported to perform the same function. In this study, we examined ...