Browsing by Author "Pantaleo, Antonella"

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Imatinib augments standard malaria combination therapy without added toxicity

Huynh, Dinh Chien; Turrini, Francesco; Low, Philip S.; Tran, Anh Tuan; Putt, Karson S.; Noomuna, Panae; Kesely, Kristina R.; Pantaleo, Antonella (2021)

To exit its erythrocyte host, the malaria parasite Plasmodium falciparum must destabilize the erythrocyte membrane by activating an erythrocyte tyrosine kinase. Given that imatinib inhibits erythrocyte tyrosine kinases and ...
Imatinib augments standard malaria combination therapy without added toxicity

Chien, Huynh Dinh; Pantaleo, Antonella; Kesely, Kristina R.; Noomuna, Panae; Putt, Karson S.; Tuan, Tran Anh; Low, Philip S.; Turrini, Francesco M. (2021-08-26)

To egress from its erythrocyte host, the malaria parasite, Plasmodium falciparum, must destabilize the erythrocyte membrane by activating an erythrocyte tyrosine kinase. Because imatinib inhibits erythrocyte tyrosine kinases ...