Browsing by Author "Tran, Thi Trang Uyen"
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and keratinocytes belongs to UCMSC-derived exosomes. Data from this study indicated that BMMSCs and UCMSCs under clinical condition secreted exosomes are promising to develop into therapeutic products for wound healing treatment.
Nguyen, Dac Tu; Hoang, Diem Huong; Nguyen, Hoang Phuong; Do, Thi Xuan Phuong; Dang, Van Duc; Nguyen, Xuan Hung; Dam, Thi Minh Phuong; Bui, Thi Hong Hue; Trinh, Mai Quynh; Vu, Duc Minh; Hoang, Thi My Nhung; Nguyen, Thanh Liem; Tran, Thi Trang Uyen (2020-06-24)Exosomes are nano-scale and closed membrane vesicles which are promising for therapeutic applications due to exosome-enclosed therapeutic molecules such as DNA, small RNAs, proteins, and lipids. Recently, it has been ... -
Differential Cytotoxicity of Curcumin-Loaded Micelles on Human Tumor and Stromal Cells
Do, Xuan Hai; Hoang, Thi My Hanh; Vu, Anh Tuan; Nguyen, Lai Thanh; Bui, Thi Thuy Dung; Dinh, Duy Thanh; Nguyen, Xuan Hung; Mai, Thi Hien; To, Thanh Thuy; Nguyen, Ngoc Huong Tra; Hoang, Thi My Nhung; Tran, Thi Trang Uyen (2022-10-15)Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. ... -
Differential wound healing capacity of mesenchymal stem cell-derived exosomes originated from bone marrow, adipose tissue, and umbilical cord under serum- and xeno-free condition
Hoang, Diem Huong; Nguyen, Dac Tu; Nguyen, Hoang Phuong; Nguyen, Xuan Hung; Do, Thi Xuan Phuong; Dang, Van Duc; Dam, Thi Minh Phuong; Nguyen, Thanh Liem; Tran, Thi Trang Uyen (2020-06-24)Exosomes are nano-scale and closed membrane vesicles which are promising for therapeutic applications due to exosome-enclosed therapeutic molecules such as DNA, small RNAs, proteins, and lipids. Recently, it has been ... -
Effects of Extracellular Vesicles Secreted by TGFβ-Stimulated Umbilical Cord Mesenchymal Stem Cells on Skin Fibroblasts by Promoting Fibroblast Migration and ECM Protein Production
Vu, Duc Minh; Nguyen, Van Tinh; Nguyen, Thu Huyen; Do, Thi Xuan Phuong; Dao, Huy Hoang; Do, Xuan Hai; Le, Nhi Thi; Nguyen, Xuan Hung; Tran, Thi Trang Uyen (2022-07-27)Umbilical cord-derived mesenchymal stem cells (UCMSCs) have been illustrated for their roles in immunological modulation and tissue regeneration through the secretome. Additionally, culture conditions can trigger the ... -
Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoarthritis Treatment: Extracellular Matrix Protection, Chondrocyte and Osteocyte Physiology, Pain and Inflammation Management
Nguyen, Thu Huyen; Duong, Chau Minh; Nguyen, Xuan Hung; Tran, Thi Trang Uyen (202-10-26)Osteoarthritis (OA) is a prevalent degenerative disease characterized by persistent pain and restricted motion. In recent years, mesenchymal stem cells (MSCs) have emerged as a promising alternative therapy for OA due to ... -
Mesenchymal stem cell-derived extracellular vesicles for osteoarthritis treatment: extracellular matrix protection, chondrocyte and osteocyte physiology, pain and inflammation management
Nguyen, Thu Huyen; Duong, Minh Chau; Nguyen, Xuan Hung; Tran, Thi Trang Uyen (2021)Osteoarthritis (OA) is a common degenerative disease that can lead to persistent pain and motion restriction. In the last decade, stem cells, particularly mesenchymal stem cells (MSCs), have been explored as a potential ... -
Optimization of human umbilical cord blood-derived mesenchymal stem cell isolation and culture methods in serum- and xeno-free conditions
Nguyen, Thanh Liem; Tran, Trung Nghia; Tran, Thi Trang Uyen; Nguyen, Quang Minh; Tran, Minh Anh; Do, Thi Xuan Phuong; Chu, Thi Thao; Nguyen, Dac Tu; Bui, Viet Anh; Ngo, Anh Tien; Hoang, Thanh Van; Hoang, Thi My Nhung (2022)Background: Although umbilical cord blood (UCB) is identified as a source of mesenchymal stem cells (MSCs) with various advantages, the success in cell isolation is volatile. Therefore, it is necessary to optimize methods ...